Membrane Potential and Intracellular Ca Oscillations Activated by mGluRs in Hippocampal Stratum Oriens/Alveus Interneurons
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چکیده
Woodhall, Gavin, Christine E. Gee, Richard Robitaille, and (McBain and Dingledine 1993; Morin et al. 1996; Sah et al. Jean-Claude Lacaille. Membrane potential and intracellular Ca 1990). Interneurons of the hippocampal CA1 region receive oscillations activated by mGluRs in hippocampal stratum oriens/ major excitatory inputs from CA3 and/or CA1 pyramidal alveus interneurons. J. Neurophysiol. 81: 371–382, 1999. Metabocells (Blasco-Ibanez and Freund 1995; Lacaille and tropic glutamate receptors (mGluRs) are expressed heterogeSchwartzkroin 1988; Lacaille et al. 1987; Maccaferri and neously in hippocampal interneurons, and their signal transduction McBain 1995). These synapses bear N-methyl-D-aspartate cascades remain largely unclear. We characterized an oscillatory (NMDA) and a-amino-3-hydroxy-5-methyl-4-isoxazoleresponse activated by the mGluR agonist 1S,3R-1-aminocyclopenpropionic acid (AMPA) glutamate receptors subserving fast tane-1,3-dicarboxylic acid (1S,3R-ACPD) in hippocampal inter-
منابع مشابه
Membrane potential and intracellular Ca2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons.
Metabotropic glutamate receptors (mGluRs) are expressed heterogeneously in hippocampal interneurons, and their signal transduction cascades remain largely unclear. We characterized an oscillatory response activated by the mGluR agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in hippocampal interneurons of stratum oriens-alveus (OA) with simultaneous whole cell current-clamp...
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